miRNA expression profiles in Smad4-positive and Smad4-negative SW620 human colon cancer cells detected by next-generation small RNA sequencing

Wei Yan, Zhongcai Liu, Wenchao Yang, Guoyang Wu Department of General Surgery, Zhongshan Hospital, Xiamen University, Xiamen, Fujian 361004 People’s Republic of China Background and aims: SMAD4, as Tattooing Supplies a tumor suppressive gene in human colon cancer, inhibits the metastasis of colon adenocarcinoma cells.However, the molecular me

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Measurement and modeling of excess pore-water pressure in warm saturated frozen soil based on dynamic loading effect

Measuring pore-water pressure (PWP) in frozen soils poses significant challenges in geotechnical testing experiments, and understanding PWP is crucial for AUSHIS unraveling the mechanism of frost heave generation in cold regions.This paper aims to clarify the development pattern of PWP in frozen soil through laboratory tests, specifically focusing

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Self-efficacy in protecting oneself against HIV transmission: A qualitative study of female university students in Malawi

This article deals with the complexity of health behaviour from a self-efficacy perspective, and shows the naivety in assuming knowledge as the main guide to better protection against HIV.The authors accentuate the importance of local knowledge when developing health strategies as in the case of protection against HIV, in this case for female unive

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